Sentence examples for binding was not mediated from inspiring English sources

We found that EAEC strain 042 has the ability to bind directly and indirectly to integrin α5 β1; direct binding was not mediated by AAF/II fimbriae and indirect binding was mediated by AAF/II and fibronectin.

Furthermore, the interaction between Tim and Plk1 was insensitive to Dnase I treatment, indicating that the binding was not mediated by non-specific DNA or chromatin linkages (Fig. S1).

Similar results were obtained after expression of the Rup1 Y135F mutant in a ubp2Δ deletion mutant background (data not shown), indicating the residual binding was not mediated by Ubp2.

We show that p53 binds BRD4 but that this interaction is not disrupted by JQ1, implying that binding is not mediated by either of the two bromodomains.

We show that Swc2 is required for Swr1 binding to chromatin, and that this binding is not mediated by its interaction with Htz1 because it is not prevented by htz1Δ.

This also suggests that PLSCR1 binding is not mediated by a linear motif contained within the SLPI primary sequence, but is rather related to the recognition of the conformational structure of the WAP domains.

The data presented thus far indicated that UBXN7 binding to CUL2 was not mediated by its interaction with ubiquitylated-proteins that are CRL2 substrates.

This effect was not due to direct peptide binding of LPS and was not mediated through the anti-inflammatory receptors MC1R or MC3R.

In addition, we were able to confirm that this increased EC monolayer breakdown was not mediated by binding of CXCL9 ligand to the CXCR3 receptor presented by ECs, but due to the ligand/receptor interaction on melanoma cells.

Resistance was not mediated by altered binding of drugs to DNA or by increased repair of DNA damage.

PDGF-Ralpha up-regulation was not mediated by the IL-1R system and was independent of LPS-binding proteins in serum.