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Importantly, the increase in NIR-conPK specific binding was not associated with a change in TSPO protein and mRNA (Fig. 3C and Fig. S3A).
In studies with field isolates from Asia, however, ICAM‐1 binding was not associated with severe malaria (Ockenhouse et al., 1991; Udomsangpetch et al., 1996).
Considered in toto, GATA2 binding was not associated with any particular expression trajectory during erythroid differentiation, but stratification by DNA motifs linked binding of GATA2 at GATA repeat/palindrome sequences to downregulation of gene expression.
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However, detailed analyses of HP1 distribution using cytoimmunochemical approaches and high resolution mapping based on the DamID technique have shown that although HP1 and the H3K9me2 mark generally overlap in the chromocenter and pericentric regions, there are also numerous sites on the chromosome arms where HP1 binding is not associated with di- or trimethylation of H3K9.
This binding is not associated with miRNA production or RNA cleavage.
This suggests that Rinl binding is not associated with MuSK activation.
This binding is not associated with miRNA biogenesis or RNA cleavage but correlates with the level of gene expression.
In Asia, ICAM1 binding is not associated with severe malaria in field-isolate studies (Refs 35, 72), and ICAM1 polymorphisms have not been studied.
A recent Cameroon study also found that seroreactivity to the CSA-binding region was not associated with gravidity.
In a candidate gene approach, Vitamin D-binding protein (VDBP) genotype was not associated with (multiple) BCC development, except possibly in the youngest age-group (A/T variant of rs7041 was associated with; adjusted HR = 1.88, 95% CI 1.10 3.20), whereas homozygote Gc1s carriers had a significantly lower BCC risk; adjusted HR = 0.53, 95% CI 0.31 0.91) [ 113].
IGF-I was not associated with either of the two binding proteins, nor with IGF-II.
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