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Interestingly, BRCA1 binding was increased at the AP endonuclease (APEX), Ras homolog gene family member G (ARHG) and the growth arrest and DNA damage inducible family member G (GADD45G) when BRCA1 is hypomethylated (Figure 4b).
Since in the presence of control-siRNA NFIX binding was increased at 39°C, this showed that heat shock increases NFIX recruitment to the HSF1 promoter in a CGGBP1-dependent manner.
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First, we confirmed that Meis binding is increased at these regions in the IIBA.
Hyaluronan binding was increased in cells transfected with either CD44S or CD44E.
Interestingly, the transcript abundance of a gene UBP1 interacting protein 2a (UBA2a) with homology for a RNA-binding protein AKIP1-like protein (VVTU19049_s_at) was increased at EL 36.
Therefore, it remains unclear if simply the overall affinity of Bim1 for microtubule binding is increased or if indeed the relative accumulation at microtubule ends compared to the lattice is reduced/is now absent (as the authors conclude).
Relative sensitivity to perturbations in parameters for binding of therapeutics and binding processes with which therapeutic binding competes were increased at these lower drug concentrations due to the fact that drugs are in greater competition for binding to receptors when drug concentrations are reduced.
The activation model predicts that one would find equal amounts of the three proteins at short and long telomeres (but see below), whereas the recruitment model predicts that Est2 binding should be increased at the short versus long ends.
AR protein was significantly increased at 3 h post-exercise and decreased at 24 h post-exercise for ULB, whereas AR DNA binding was significantly increased at 3 and 24 h post-exercise (p < 0.05).
There was increased binding of PCAF at the FOS promoter at the tolerated 0.5-μM dose and at the toxic 2.5-μM As2O3 dose.
viridis reaction centres for the normally weakly-binding DCMU can be increased by at least four orders of magnitude through a single tyrosine to phenylalanine change in a residue close to the QB binding pocket (Sinning et al., 1989).
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