The results show that mutp53 was not bound to a canonical wtp53 target gene promoter (that is, Puma) in SKBR3 control cells, while the binding was enriched after Zn II -curc treatment; in an opposite way, the binding to gene promoters, target of mutp53 (specifically, MDR1 and cyclin B2), was reverted after Zn II -curc treatment, as previnusly reported.
The change of the binding stringency indicates that the ssDNA pool was enriched after the end of the screening process.
We found that TBX3 binds the Tbx2 promoter and that this binding is enriched upon depletion of JARID2, which induces TBX3 expression (Fig. 8d).
(c) FOSL1 binding is enriched in the chromatin regions with increased interactions in stimulated CD4+ T cells, while no enrichment is detected in resting CD4+ T cells.
esBAF binding is enriched at sites bound by the general pluripotency regulators OCT4, SOX2, and NANOG, consistent with previous work demonstrating that BRG1 facilitates the binding of these factors to their target sites12.
Within the category molecular function, binding-related sub-categories such as cation binding, ion binding, and nucleoside binding were enriched.
Finally, among Molecular Function terms, 'nucleotide binding'hydrolaseactivityvity' and 'RNA binding' were enriched in non-conserved gene-like sequences.
According to molecular function, protein binding, protein tyrosine kinase activity, protein serine/threonine kinase activity, and actin binding were enriched.
The potato PPT library was enriched for zinc ion binding (GO 0008270), nucleic acid binding (GO 0003676), and transcription factor activity (GO 0003700).
While Hmo1 was enriched at RPS14B, its binding was not significantly affected in either the wild-type strain or H3K37A mutant before or after rapamycin treatment.
(A ) Adipogenic TF binding motifs are enriched at MLL4 binding regions during adipogenesis while myogenic TF binding motifs are enriched at MLL4 binding regions in myocytes.
