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The role of the F1 and F2 domains in erythrocyte invasion and binding was elucidated with mAbs.
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A role of conformation-dependent cooperative electrostatic interactions in strengthening of binding is elucidated, and changes in the copolymer hydrate structure related to the polyamine binding are discussed.
Bacteriophage endolysins typically contain two domains: an enzymatically active domain and a cell wall binding domain, some of which have been elucidated with crystal structures [ 22].
Some mechanisms remain to be elucidated with regard to the lectin activity of SBL, but the implication of binding activity against sialic acid-containing glycoconjugates is likely from the study on agglutination inhibition.
However, this has to be elucidated with additional information.
This binding ability was elucidated during studies characterizing CUG repeat RNA-binding proteins in the neuromuscular disorder DM1.
Furthermore, the interactive binding model of (S -24o with c-Met waS -24oidated by virtue of a molecular modeling study.
Its molecular-level binding mode with the three-dimensional structure of MAO-B was elucidated using an in silico docking study.
To correlate the ITC results on rAtACBP6 binding with its biological role, the spatial pattern of AtACBP6 expression was elucidated using AtACBP6pro::GUS fusions in transgenic Arabidopsis.
The structural basis of the great inhibitory potential of alkyl and aryl α-d-mannosides was elucidated in the crystal structure of the FimH receptor-binding domain in complex with oligomannose-3.
Their mechanism of inhibition was elucidated by measuring the effect on bioluminescence in a series of V. harveyi QS mutants and by DNA-binding assays with purified LuxR protein.
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