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The maximum distance between Oct4 and Sox2 binding was constrained to 3 nucleotides.
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To ensure ergodicity the process was constrained to a sphere centered on the initial ligand binding pose.
Bush was constrained to take exception to this publicly.
In Drosophila studies, "bottom" was constrained to 0, while the "top" was not constrained.
The intercept was constrained to equal zero.
Finally Troidini was constrained to 32.45 46.92 Ma, Battus was constrained to be within 17.22 29.29 Ma, Euryades was set to 7.21 16.9 Ma, and Parides constrained to 18.56 28.45 Ma [ 36].
The model was constrained to be reversible (default option).
The lifetime of C2 was constrained to ~1 ns.
Maximum activity was constrained to 1 for these fittings.
Or can be constrained to do so.
All other covariates were constrained to have standard linear effects.
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