Sentence examples for binding use of from inspiring English sources

Capillary leak, fluid loading, decreased protein binding, use of vasoactive medications and altered excretory organ function, will significantly distort the 'normal' pharmacokinetic (PK) profile of many agents [ 2].

Assembly of functional Fab was confirmed by demonstration of antigen-specific binding using antibodies of known specificity.

Binding affinities of hits were determined using radioligand binding studies measuring [H]granisetron binding using membranes of HEK293 cells expressing the human 5-HT3AR.

First, we examined nucleotide binding using analogs of ADP and ATP carrying a coumarin fluorescent reporter group in competition assays.

qPCR was used to determine binding by use of primers flanking binding site.

qPCR was used to determine binding by use of primers flanking binding site previously identified by ENCODE Projects.

Here, fluorescence-based detection provided sensitive detection of binding using minimal amounts of materials.

It should pointed out, however, that immunoblotting studies have failed to reveal a consistent pattern of binding using the sera of patients with premature ovarian failure[ 7].

Affinity for the endogenous agonist Ang II was determined by whole cell competition binding using tracer amounts of 3H-Ang II and increasing amounts of unlabeled Ang II.

The aim of our study was to characterize temperature effects on cortisol protein binding by use of an equilibrium dialysis method.

Furthermore it is a truly multiplexed assay, allowing the detection and measurement of ligand binding using a wide-range of immobilised target molecules simultaneously and in real-time.