Sentence examples for binding triggers conformational changes from inspiring English sources

In many EF-hand-containing proteins, calcium binding triggers conformational changes that can subsequently allow the EF-hand motif to interact with another region of the same protein or with a binding partner.

This binding event triggers conformational changes in Env, followed by interactions of Env with coreceptor CCR5 or CXCR4.

Ligand binding to a receptor triggers conformational changes that facilitate receptor dimerization and/or phosphorylation of numerous residues.

Binding of gp120 to CD4 triggers conformational changes responsible for binding to the coreceptor.

The proton binding or dissociation at this residue triggers conformational changes of the cytoplasmic domain of MotA in the stator, which are believed to drive the flagellar rotation through interactions between MotA and FliG.

During HIV-1 entry, binding of the gp120 Env to the initial receptor, CD4, triggers conformational changes in Env that result in the formation and exposure of the highly conserved gp120 site for interaction with the coreceptors, CCR5 and CXCR4.

Upon ligand binding, two tyrosines in the conserved JMS are phosphorylated, which triggers conformational change of the JMS and releases this segment from an inhibitory interaction with kinase domain.

Ca2+ binding by Miro is proposed to trigger conformational changes that disrupt the interaction between Kif5 and MTs or Milton/TRAK and Kif5 and, consequently, disrupt mitochondrial transport [ 98, 99].

Histidine residues have been implicated in SCARB2's pH-dependent binding to β-GC (Zachos et al., 2012) and H150 is well positioned to act as a pH sensor for triggering conformational changes that regulate ligand binding.

Regulation of this process by Rho/Rab-GTP binding partners on the vesicle and plasma membranes may trigger conformational changes to activate assembly of the subunits [4].

Typically, binding of ATP and/or hydrolysis of ATP into ADP and Pi trigger conformational changes of SW1 and SW2, and such changes convert chemical energy into mechanical forces.