Sentence examples for binding to very from inspiring English sources

These data suggest that cell-cell interactions, mediated by stromal cell expressed VCAM-1 binding to very late antigen-4 (α4β1 integrin) on myeloma cells, are necessary for tumor cells to express RANKL.

The mutant or wild-type specific PCR amplifications take place in the same reaction tube, thereby allowing the mutant or wild-type specific PCR primers to compete for binding to very limited templates.

The latter finding is consistent with the notion that RANKL levels are modulated by stromal cell-expressed VCAM-1 binding to very late antigen-4 on myeloma tumor cells [ 5].

Thereby it has to be noted that primer binding to the very large palindromic structure was kinetically calculated to be preferred to re-annealing of the elongated hairpin.

We also determined that 16 f– g and 17 f– g inhibit colchicine binding to tubulin very effectively.

Indeed, HSQC spectra are some of the most diffused tools in NMR-based screening to monitor protein binding to even very low affinity ligands.

The most readily interpreted results on the glycan array are those that reflect binding to a very limited set of glycans that clearly share a structural motif.

Alternatively, it may be due to MCAK binding to some very long microtubules in the reaction mix and failing to reach the end, where ADP release is maximally accelerated (see below).

Using a semi-quantitative approach similar to that employed for binding of antibodies to other cell surface antigens (Leite et al., 2008; Waters et al., 2008), the binding was scored visually from 0 (no binding) to 4 (very strong binding) by two independent observers.

The importance of the C-terminal part of TFPIα in non-hemostatic activities has previously been reported both in vivo [ 24] and in vitro [ 18- 24], and TFPIα has been shown to be able to inhibit cell proliferation by binding to the very low density lipoprotein receptor (VLDLR) through its Kunitz-3 and C-terminal domains [ 19].

Although at first sight the behavior of aS upon binding to CR appears very similar to that seen for binding of the protein to very low concentrations of phospholipids, a key difference is seen in the kinetics of the process.