Sentence examples for binding to this sequence from inspiring English sources

PTB binding to this sequence is dependent upon phosphorylation by protein kinase A and is blocked if the CU-rich sequence is mutated to a U-rich region.

Moreover, this dependency is due to direct interaction of SpRunt-1 with its target sequence in module C, as substitution of two base pairs essential for Runx binding to this sequence (Fig. 4C) abolishes blastula stage module C activity (ModCΔRunx; Fig. 4E).

Irrespective of RNA editing function, a factor binding to this sequence, either on DNA or RNA, could provide such a selective force.

Other groups have already suggested an important role for the HNF1 binding site [ 22- 24], and in vitro HNF1 binding to this sequence has been demonstrated by gelshift assays [ 24].

The 3′ region of the intron also possessed putative Sp1 binding sites (oligo-6); however, no transcription factor binding to this sequence was observed using the same method (data not shown).

Furthermore, we have shown Fur binding to both this sequence and to its own promoter, indicating a direct role of the Fur protein in the regulation of class Ib nrd genes as well as in the autoregulation of fur expression similarly to what has previously been described in E. coli [23].

The conjugates at 303, 153, 745 and 764 are all located on elements (the N-terminal domain and promoter recognition loop) which participate in sequence specific binding to this upstream, recognition half of the promoter.

As the Y-box promoter element is crucial to the regulation of MHC class II gene expression, sequence-specific binding to this motif indicates a potential role for DEK in modulating normal and abnormal immune response.

Here, we have detected no binding of FOXL2 to this sequence or to any other close sequence in our ChIP-Seq analysis.

Since the 9d-encoded C-terminus is also present in smTM and in TM5a, one might suppose that the different binding is related to this sequence.

Our reporter gene assay and ChIP results show that the ERE-associated sequence at 21q22.3 has regulatory activity and that rs2839494 and rs1078272 in this region are able to affect the binding of this sequence to ERα and Rad21, respectively, resulting in a difference in ERα-activated expression of the reporter gene and suggesting that Rad21 promotes ERα-regulated transcription.