Sentence examples for binding to this region from inspiring English sources

Taken together, these results reveal that H3K9ac may contribute to activate HIF-1α transcription by binding to this region containing CpG/non-CpG surroundingunding the TSS.

These results, without undermining the strength of BCL11A as a silencer of the γ globin gene, suggest that the LCR background, by governing the state of BCL11A binding to this region, plays a more significant role in determining the thalassemia phenotype than the level of BCL11A protein expression, that might be influenced by single nucleotide polymorphisms in intronic regions of the BCL11A gene.

Ca2+/calmodulin binding to this region initiates Ca2+-dependent fast inactivation of TRPV6, which can be reversed by PKC dependent phosphorylation [47].

Though the binding to this region may represent an additional mechanism through which PHOX2B promotes ALK transcription, it may be also due to an indirect effect of PHOX2B over-expression on this proximal portion of the ALK promoter.

We identified a region of the elastin protein that had more immunogenic properties; the different level of IgG binding to this region among the responders, which were classified as such if their OD was above the threshold set at the highest background, was of (9,9) and no responders (19,12), for control and EO-COPD respectively.

As previously mentioned, the basis for antibody cross-reactivity with EBNA-1 and dsDNA does not appear to be charge interactions since removal of the negatively charged amino acids from the carboxyl region of EBNA-1 does not diminish binding to this region (Figure 7).

EthR has been shown to repress transcription of the activator gene ethA by binding to this intergenic region, thus contributing to ethionamide resistance.

Independent ChIP analysis confirmed this results, showing ERβ binding to this same mtDNA region upon activation by E2 or its selective agonist 2,3-bis(4-hydroxyphenyl) propionitrile (DPN) and lack of ERα binding.

This product was comparable to the positive control PCR product obtained using primers that amplified the known start site in the GAPDH gene, suggesting significant TBP binding to this proximal TATA-containing region of the promoter.

Like other TFs, OmpR may prevent binding of other repressors or directly activate transcription by recruiting RNAP, or exclude RNAP binding at this region to repress transcription.

They also decreased tryptophan fluorescence of the isolated C-terminal region, indicating binding to this domain.