Sentence examples for binding to their postsynaptic from inspiring English sources

Neurexins (Nrxs) are presynaptic membrane proteins with a single membrane-spanning domain that mediate asymmetric trans-synaptic cell adhesion by binding to their postsynaptic receptor neuroligins.

spikes are propagated to their postsynaptic targets with a delay δ.

For example, any rods that have lost their outer segment will hyperpolarize, providing tonic depolarization to their postsynaptic RBCs.

GCaMP imaging revealed that kif5aa mutant RGCs do not transmit signals from the retina to their postsynaptic partner cells.

This observation indicates that the population of immature GC has a higher capability to retransmit temporal information to their postsynaptic targets than the population of mature neurons.

Synaptic elements and postsynaptic densities were heterogeneously distributed throughout the different hippocampal layers as revealed by the use of serial EM sections, which allowed us to distinguish and quantify different synapse populations, according to their postsynaptic densities and synaptic vesicles composition (see Supplementary Figure S1).

Many in vitro studies support a model in which modifiable synapses detect presynaptic activity through glutamate binding to postsynaptic receptors and detect postsynaptic activity through depolarization, which relieves magnesium block of N-methyl-D-aspartate (NMDA) receptors (NMDARs) and activates voltage-gated calcium (Cav) channels.

We review research on one major family of postsynaptic adhesion molecules, neuroligins, which bind to their presynaptic partner neurexin across the synaptic cleft.

The end-plate potentials (EPPs) that are the depolarizations of skeletal muscle fibres caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction are facilitated initially, followed by a depression.

Neurexins mediate synapse formation by trans-synaptic binding to several postsynaptic partners including neuroligins, LRRTMs and GluRδ2 [9]–[15].

Wg acts through the Fz2 nuclear import pathway (Mathew et al., 2005): Wg binding to postsynaptic Fz2 receptors stimulates receptor internalization and cleavage of the C-terminus (Fz2-C), which translocates to postsynaptic nuclei to control ribonucleoprotein (RNP) export and local translation (Fig. 3) (Speese et al., 2012).