Sentence examples for binding to their own from inspiring English sources
Hes genes encode nuclear proteins that act as transcriptional repressors and negatively regulate their expression via direct binding to their own promoter [ 97].
IL-11 is a member of the IL-6 family that recruits a homodimer of gp130, a promiscuous 130 kDa β subunit, after binding to their own non-signaling ligand-specific receptor, IL11R [ 8, 9].
This triad also forms an autoregulatory circuit, in which, by binding to their own promoters, as well as to the promoters of Oct4, Sox2 and Nanog they collaborate to sustain their expression.
In eukaryotic cells, RPL2, RPL30, RPS14, and RPS28 were reported to function by binding to their own transcripts or some other mechanisms to perform regulation of ribosomal protein production.
Thus it is plausible that such potent effects of TRAIL in inducing poststroke neuronal death is also related to redundancy with two cytokines, TNF- α and FasL, possessing similar properties, therefore potentiating TRAIL-induced neuronal death, via binding to their own death receptors.
Additional complex information is also provided, such as the visualization of intragenic miRNAs within their host genes and positioning along the isoforms, expression correlation between intragenic miRNAs and their host genes, intragenic miRNAs binding to their own host genes and intragenic miRNAs binding to genes that are directly interacting with their host genes.
Furthermore, TRAF3 and TRAF6 independently bind to their own specific binding sites in IPS-1 [25], [25].
"The Coens have again taken a real time and place and freely made it their own, drawing on actual persons and events for inspiration, but binding themselves only to their own bountiful imaginations," wrote Scott Foundas of Variety in one of the film's first reviews posted online.
The binding of LNX1/LNX2 to their own carboxy-termini might serve to regulate their interactions with such ligands.
However, since the recommendation is not legally binding, researchers should refer to their own national legislation for specific requirements.
In the case of PEST domain-containing phosphatases, including PTPN12, PTPN18 and PTPN22, the PEST domains are reported to mediate their substrate binding, but not related to their own ubiquitiantion or degradation.
