Sentence examples for binding to their appropriate from inspiring English sources
Like the majority of neoplastic cells, HCC secrete an array of inflammatory cytokines that exert their multiple, partially overlapping functions (mitogenic, motogenic, angiogenic) in a para-/autocrine manner via binding to their appropriate receptors.
CaN is inhibited by drugs such as CsA and FK506 through the binding of these drugs to their appropriate receptors (immunophilins) [31].
This unusual shape prevents ribosomes--the button-shaped organelle that zips along the messenger RNA and strings together amino acids into proteins--from binding to the appropriate piece of RNA.
Activation of the pathway is initialized by an agonist binding to the appropriate GPCR which has greater affinity for the Gs protein.
The optimal activation of NF-κB, allowing its binding to the appropriate promoter regions, requires phosphorylation in the transactivation domain of the p65 protein.
It is widely assumed that G protein-coupled receptors and among them, the melatonin receptors, share the same structure as rhodopsin in which predicted critical residues for ligand binding to the appropriate binding pocket are located in the transmembrane regions [ 29].
In both cases, β-catenin exercised its activity by binding to appropriate DNA promoter regions.
MicroRNAs (miRs) represent small non-coding RNAs of about 20 to 22 nucleotides, which, upon sequence-specific binding to appropriate mRNAs, repress the translation of the corresponding proteins or induce a subsequent degradation of the miR/mRNA complexes.
Recently, evolutionary analyses of large sets of transcription factor binding sites have highlighted the importance of considering the binding affinity or strength of the binding sites for their appropriate transcription factor [ 10, 11, 13, 18].
VIVIT peptide competes with NFATc for binding to calcineurin and is appropriate to inhibit NFATc dephosphorylation in cell-free assays.
Transcription factor binding to DNA requires both an appropriate binding element and suitably open chromatin, which together help to define regulatory elements within the genome.
