Sentence examples for binding to the triple from inspiring English sources
To summarize, the same loop at the N-terminus of the LARA domain appears involved in (1) positioning the foot in respect to the rest of the leg so that to allow for equivalent interaction with both the inner and the outer LdcI rings, (2) binding to LdcI, and (3) binding to the triple helical bundle of the adjacent RavA.
The change in the axial D-periodicity and helical rise per residue also indicates that the process of IPA-collagen interaction involves IPA molecules binding to the collagen triple helix and when in sufficient quantity causing distortion of the collagen molecular structure.
In our opinion, however, the reported data for HSP47 binding to triple helical peptides [17], [19], [40] and to collagen [15], [35] do not support the cooperative binding model proposed in [15].
We confirmed that our monoclonal antibodies were conformation dependent; that is, they were restricted to binding the triple-helical CII epitopes in the triple-helical state only, and bound to the rCII peptides containing their specific epitope.
More recent data, however, provide a compelling evidence of preferential HSP47 binding to triple helices compared to weak or negligible binding to unfolded chains [19].
This can be correlated with binding of the triple E mutated occludin to ZO-1 and its efficient integration into TJs as detected by increased distribution to the TX-100 insoluble fraction.
These experiments visualised DDR2 bound to the triple helix of collagen type I, but did not identify specific binding sites.
Road to the Triple Crown.
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The cause of this bias is most likely a lack of probe saturation in low DNA quantity samples and inflated intensities due to a higher binding affinity of the triple hydrogen bonding of guanine to cytosine.
The additional T60D and S64D mutations mediated progressive loss of RPA binding, and the triple S23D/T60D/S64D mutant retained only about 40% of the RPA-binding capacity relative to WT UNG2.
