Sentence examples for binding to the third from inspiring English sources

This is done in particular for a set of related sequences binding to the third PDZ domain of PSD-95 with encouraging results.

It has been shown that nuclear Cyclophilin33 (CYP33) mediates this transition by binding to the third PHD finger (PHD3) of MLL (16).

The absence of strong binding to the third site implies distortion of this remaining site, and hence of the UspA1 molecule.

SEM and TEM showed violent membrane blebbing of apoptotic cells (zeiosis), and fragmentation of DNA creating a vacuolar nucleus due to calicheamicin-damaging action after binding to the third end of oligopurine tracts causing strand breaks.

Two of the three putative binding sites in Smc3 (WIS1 and WIS2) have been previously identified as being functionally important in either Smc3 or related ABC ATPases, and in this work, we show that mutations that are predicted to weaken binding to the third site involving the WIS3 demonstrate strong in vivo phenotypes.

We concluded that LDLA-box 2 binding to the second 14-3-3 14-3-3 14-3-3an intriguing observation with protomer implications for ExoS regulation.

These modifications hinder the TRIM25 binding to the first CARD and the K-63-linked polyubiquitination of the Lys-172 of RIG-I.

We stimulated intestinal organoids with Notch ligands and inhibitors and discovered that intestinal stem cells employ a positive feedback mechanism via direct Notch binding to the second intron of the Notch1 gene.

These findings indicate that the first nine ZFs of the BORIS DNA binding domain are required for binding to the sixth CTCF target site in the IGF2/H19 ICR in vitro.

Interestingly, the scFvs developed here showed good binding to the breast cancer cell line T47D and ovarian cancer cell line SKOV3, but no binding to the second breast cancer cell line MCF-7.

Therefore, bound antigens should be almost opposed in the diabody, and in a small circular area in the minibody, which actually precludes the binding to the second antigen in a number of situations.