These are drugs, like Fosamax and Actonel, that protect against osteoporosis by permanently binding to the surface of bone and slowing the activities of osteoclasts, cells that break bone down.
We also demonstrate the ability of these devices to monitor protein layers binding to the surface.
PLA2 activity strongly increases upon binding to the surface of aggregated phospholipid.
To investigate glycodelin (Gd) binding to the surface of sperm cells in relation to sperm morphology and seminal plasma Gd.
Cell-surface engineering with poly[ethylene glycol] (PEG) derivatives can successfully prevent antibody binding to the surface antigens.
In the case of DDOA, binding to the surface of nanoparticles occurs only through the -COOH group as it does not contain a double bond.
An antibody can induce a much greater aggregation of GNRs by binding to the surface of C. neoformans cells resulting in a much higher attenuation values than ever.
Figure 5 compares spectra taken before and after the peptide functionalization and finally after the RC binding to the surface of PSiMc.
Moreover, Raman spectroscopy enable observe if the protein binding to the surface occurs via free amino groups or through cysteine residues.
These results provide, to our knowledge, the first evidence of ligand binding to the surface crevice and cavity of the protein in solution.
A new method for producing label-free high-resolution images of biomolecular binding to the surface of a biosensor is demonstrated.
