Sentence examples for binding to the sixth from inspiring English sources
These findings indicate that the first nine ZFs of the BORIS DNA binding domain are required for binding to the sixth CTCF target site in the IGF2/H19 ICR in vitro.
We concluded that LDLA-box 2 binding to the second 14-3-3 14-3-3 14-3-3an intriguing observation with protomer implications for ExoS regulation.
This is done in particular for a set of related sequences binding to the third PDZ domain of PSD-95 with encouraging results.
These modifications hinder the TRIM25 binding to the first CARD and the K-63-linked polyubiquitination of the Lys-172 of RIG-I.
We stimulated intestinal organoids with Notch ligands and inhibitors and discovered that intestinal stem cells employ a positive feedback mechanism via direct Notch binding to the second intron of the Notch1 gene.
Interestingly, the scFvs developed here showed good binding to the breast cancer cell line T47D and ovarian cancer cell line SKOV3, but no binding to the second breast cancer cell line MCF-7.
Therefore, bound antigens should be almost opposed in the diabody, and in a small circular area in the minibody, which actually precludes the binding to the second antigen in a number of situations.
As shown in Fig. 6B, a mutation of binding site 1 almost completely abolished the activity of miR-222, whereas a mutation of binding site 2 only slightly reduced miR-222 activity, indicating that the majority of miR-222 activity is due to the binding to the first consensus sequence.
Interaction with the first attI1 substrate leads to cooperative binding to the second attC site (B2), thus allowing the recruitment of a second IntI1 dimer on the second strand of the attC site (B3) and the formation of the tetrameric intermediate, which in turn stabilizes a ssattC structure (B4) leading to the catalysis of the strand exchange between dsattI1 and bsattC (B5).
STAT5 represses Igκ recombination by binding to the second recombination enhancer, iEκ (Malin et al, 2010).
