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Active NPFs bind to the actin-related protein (Arp) 2/3 complex and promote its binding to the side of an existing actin filament, a reaction that allows the Arp2/3 complex to nucleate a new actin filament as a branch on the old filament (3, 4).
CBH I and LPMO both showed pronounced ( ≥ 4-fold) preference for binding to the side walls of the cellulose nanocrystals, as compared to binding to the nanocrystals' top surface.
More recently, a model of STA-21 interaction with the Stat3 SH2 pY-peptide binding pocket has been proposed, which featured the 1-oxygen of STA-21 binding to the side chain ammonium hydrogen of R609 within the pY-residue binding site.
When isolated from most species, the complex is inactive, and activation requires binding to the side of a preformed actin filament and association with a nucleation promoting factor (NPF) protein (Pollard, 2007; Achard et al., 2010).
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It is worthwhile to note that the Kd values for binding to the side-chain amide protons are approximately 3- to 4-fold larger than those of the backbone ones at the same condition, indicating that anions interact with backbone and side-chain amide protons separately.
10a Again, those water molecules share the same binding motifs: HOH794 binds to the side chain carboxamide NH of Asn 194, and HOH822 binds to the backbone NH of Phe 231 as well as to the side chain amino functionality of Lys 119.
Comparison of protein in two different orientations with linkers binding to the opposite sides of the protein demonstrates the possibility of utilizing the constructed surfaces as photoelectronic devices.
E37 and E42 are located in a loop region that undergoes a conformational change upon Zn II) binding to bring the side chain of E42 into the proximity of the bound Zn II).
We interpret the mass changes during the injection of vesicles as lipids binding to the AUT functionalized side of the cantilevers.
Furthermore, while binding to the species at one side of the equilibrium might disturb the equilibrium through thermodynamic linkage, reliable kinetic parameters of amyloid fibril formation can still be obtained.
Add seam binding to the inside of a side seam or waistline.
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