Sentence examples for binding to the shared from inspiring English sources

First, FXR and PPAR α compete for binding to the shared direct repeat 1 (DR1) sites, with opposite transcriptional outcomes on the expression of autophagy genes.

Twist1 occupancy at shared binding regions associated with Chst11, Litaf, Ror2 (Ror-a, a region 15,965 bp upstream from the TSS ), and Spata5 was confirmed in ECCs, limb buds, and PNST cells, but binding to the shared CD44 site was not detected.

Analysis of the transcription factors binding to the identified cis-regulatory elements shared between the OsEULs and their co-expressed genes (OsEUL regulons) retrieved two major transcription factor families involved in stress response and development, in particular the WRKY family and the basic leucine-zipper (bZIP) family.

Type I interferons (IFNs) elicit antiviral, antiproliferative and immunmodulatory responses by binding to a shared cell surface receptor comprising the transmembrane proteins ifnar1 and ifnar2.

It does so by binding to their shared p40 subunit, therefore blocking the interaction with their cognate receptors.

Overall, this result suggests that dMyc regulates the expression of miR-308 and its host gene, RpS23, by binding to their shared locus.

To explore potential contributions of c-FOS and MITF to mast cell-specific binding of the shared TFs, ChIP-Seq experiments were performed for both c-FOS and MITF in primary mast cells.

4E-BPs and eIF4G compete for binding to the eIF4E dorsal surface via a shared canonical 4E-binding motif, but also contain auxiliary eIF4E-binding sequences, which were assumed to contact non-overlapping eIF4E surfaces.

Two major factors are closely related to CRM functionality: transcription factor (TF) binding and the shared chromatin epigenetic profiles [ 3, 7- 9].

RREB1 binding to shared Twist1 binding region sequences associated with Spata5, Ror2 (Ror2-a), Litaf, and Chst11 was detected in PNST cells, and RREB1 bound to Spata5 and Litaf Twist1 binding regions in limb buds.

Whereas addition of H3K4me3 peptide had no effect, pre-incubation with RbBP5 peptide prevented HOTTIP binding to WDR5, thus confirming the shared binding cleft.