Sentence examples for binding to the regulatory from inspiring English sources

The interaction with lipids and calcium activators is mediated by binding to the regulatory domains C1 and C2.

Overexpressed Δ133p53 prevented FL-p53 from binding to the regulatory regions of p21WAF1 and miR-34a promoters, providing a mechanistic basis for its dominant-negative inhibition of a subset of p53 target genes.

An A-kinase anchor proteins (AKAP) have the function of binding to the regulatory subunits (RI and RII) of protein kinase A (PKA) and confining the enzyme to discrete locations within the cell.

We observed Stat1-nucleolin association, nuclear translocation and specific binding to the regulatory DNA element GAS.

It is part of a region necessary for the recruitment of HapX to the Hap complex and in subsequent binding to the regulatory sequence [62].

First, mutations in both α and β isoforms of the scaffolding subunit result in compromised binding to the regulatory or catalytic subunit of PP-2A.

Yuki K, Astrof NS, Bracken C, Yoo R, Silkworth W, Soriano SG, Shimaoka M. The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity.

Taken together, these findings show that C/EBPβ up-regulates Vegf gene expression through the binding to the novel regulatory region in rat Vegf promoter region in GCs undergoing luteinization.

DsxF and DsxM act as activator and repressor, respectively, by binding to the same regulatory sequences (reviewed in [29]).

During hypoxic stress, HIFs are the master regulators of VEGF and function by binding to the hypoxia regulatory element (HRE) sequence within the VEGF promoter.

Taken together, it is apparent that DNMTs-induced promoter demethylation and CTCF binding to the hTERT regulatory region are closely linked to the control of hTERT expression by SFN in breast cancer cells.