Sentence examples for binding to the region from inspiring English sources
Menin ablation abolished Cdx4-chromatin binding, while menin binding to the region was also markedly reduced due to menin excision from the cells (Fig.7A).
Wang, Bai and co-workers [39] demonstrated that NR2F2 inhibits hTERT transcription by binding to the region of the hTERT promoter at bases nt −201 to +35 that contains an E-box motif (CACGTG).
It is particularly intriguing that CSK is the only SH2 domain whose binding to the region of the blot containing EGFR decreases in both EGFR mutant cells and in cells sensitive to erlotinib.
To confirm that antibody binding to mimotope A12.2 involves interaction with a conformational epitope and thus depends on the structural integrity of the target HIV-C gp160, we compared antibody binding to the region on HIV-1 Env represented by the mimotope under native and reduced conditions.
The density of putative GRE in the promoter region may imply a probability of the GR binding to the region.
Taking these findings together, we observe Rad51p binding to the region of the hybrid-forming locus on the YAC-GALpr only when transcripts from this region are induced.
Therefore, we used EMSAs to test for evidence of cooperative binding to the regions from our ChIP-seq analysis that were bound by His10-MrpC2 as described above.
In the si-control transfected cells, we observed HDAC1 binding to the regions also bound by ZNF703, suggesting that ZNF703 may mediate active repression.
Alternatively, or in addition, suppression of RAD51 ssDNA interaction might be important for preventing RAD51 from binding to the regions of ssDNA that form during normal DNA replication.
In particular, a deletion only abolishes ligand binding to the corresponding region but not to adjacent regions.
