Sentence examples for binding to the reduced from inspiring English sources

The major repurified cytochrome c fraction showed negligible spectrophotometric differences between ascorbate and dithionite reducibility and negligible CO binding to the reduced state.

Pochapsky and colleagues identified an X-Pro cis trans isomerization redox switch in CYP101 (P450cam) that is triggered by binding to the reduced form of CYP101's cognate electron transfer partner, putidaredoxin (Pdx).

Analysis of 'Cordiale' showed only single bands binding to the ω-5 antibody in the total protein (Fig.  2E, lane 3) and monomeric gliadin fractions (Fig.  2E, lane 1), with no binding to the reduced residual protein fraction (Fig.  2E, lane 2).

These observations suggest a small perturbation of the flavin site that weakens nucleotide binding, especially when the flavin is reduced; the NADH O2 reaction is strongly inhibited by NADH binding to the reduced flavin [ 38].

Figure 2C shows that the HAR reaction is stimulated significantly by intermediate concentrations of ADP (∼6 mM) and inhibited at high concentrations, consistent with ADP binding to the reduced flavin promoting interaction of the positively charged HAR molecule by increasing the local negative charge, and by ADP inhibiting NADH oxidation at high concentrations.

Waadt et al. also report that the ABAleons made plants less responsive to abscisic acid, possibly because binding to the ABAleons reduced the amount of abscisic acid that was available to perform its role as a hormone.

Sclerostin, an osteocyte derived protein regulates osteoblast activity and sclerostin binding to the osteoblast reduces osteoblast activity.

Nonspecific protein binding to the nitrocellulose was reduced by overnight incubation at 4°C in Odyssey blocking buffer (Li-Cor, Lincoln, NE, USA).

The observation that effector peptide binding to the PHD1 domain reduces the Km for demethylation raises questions about how the liganded PHD1 domain enables enhanced interaction of the demethylase with its substrate.

Previous studies have shown that EGFR ligands may compete with mAbs for binding to the receptor and reduce their anti-proliferative activity (Castillo, 2004).

However, this inhibition does not reflect direct inactivation of QSOX or PDI, but avid binding of MVAs to the reduced unfolded protein substrates themselves.