Sentence examples for binding to the phosphate from inspiring English sources

The corresponding lysine residues in several Fatty Acyl-CoA Synthetases have been implicated in the binding to the phosphate group of ATP via electrostatic interactions [21].

In this view, during binding to the phosphate backbone the cationic side chains of the protein displace cations from the DNA ion cloud into bulk solution.

A potentially confounding issue with the active site of 6PGDH is that it contains a large number of polar residues required for binding to the phosphate, carboxylic acid and hydroxyl groups of the substrate.

Apart from helix 3, we observe sequence-specific interactions from residues in the α1 α2 loop (Y291 binding to the phosphate O of G7) and the N-terminal arm.

It has also been suggested that uranyl ions may form stable complexes with ATP by binding to the phosphate groups [ 30], thus influencing the synthesis of ATP and its cross-membrane translocation.

Animals in the Adjuphos-administered group produced a significantly higher response (p <; 0.05) than those in the Alhydrogel group possibly because the antigen could, for some reason have had a higher binding to the phosphate than to the hydroxide form.

Phosphorylation of Y1230, Y1234 and Y1235 located within the activation loop of the tyrosine kinase domain activates the intrinsic kinase activity of c-Met [ 19]. 2. Gab1 is subsequently recruited to activated c-Met by direct binding to the tyrosine phosphate residues Y1349 and Y1356 of the receptor [ 20]. 3.-7.

Our structure activity relationship (SAR) model of the interaction of polymyxin B with lipid A indicated a key role for the diaminobutyric acid (Dab) side chains for binding to the lipid A phosphate groups.

Here we report a complete biochemical and biophysical characterization of the putative M. tuberculosis dephosphocoenzyme A kinase (Rv1631) detailing the kinetic parameters of catalysis, the energetics and order of substrate binding to the enzyme and the phosphate donor specificity of the kinase.

These arginines may be involved in binding to the negatively charged phosphates of DNA.

5'-OCQA exhibits strong binding to the glycerol-3-phosphate transporter (see Table 6 and Figure 5, A).