Sentence examples for binding to the parent from inspiring English sources

Some proteins may bind to metabolites but show negligible binding to the parent compound (Hamers et al. 2008).

Binding of C3 to both ΔdltA mutants was up to 100-fold higher than C3 binding to the parent strains.

This interaction energy is significantly greater than the ΔΔ G of ∼0.6 kcal/mol associated with the difference between MEAVD and MEEVD binding to the parent TPR2A protein.

Binding of an 19F-labeled eremomycin analog in the FemA cell wall matches that of binding to the parent-strain cell wall and reveals the proximity of parallel stems in the alternating parallel perpendicular mixed-geometry model for the FemA peptidoglycan lattice.

RNA footprinting experiments suggest that the peptolide macrocycle moiety binds to the parent macrolide binding site on the E. coli ribosome with affinity that is dependent on the overall charge of the peptide tail.

To understand the properties of S4 subsite structurally, we determined the structures of wt GlpG and its F146I mutant complexed to Ac-FATA-cmk (2.9 and 2.55 Å resolution, respectively, Supplementary Table S1) and compared the ligand-binding mode to the parent structure of GlpG and Ac-IATA-cmk complex.

This represents a greater than 50-fold reduction in binding affinity relative to the parent phosphotyrosine-containing peptide, indicating that the aryl nitrogen adversely affects binding affinity.

There was no specific binding of 3H-CGP12177 thethe parent CHO cells (i.e. CHO cells without a transfected receptor).

To determine if the CD20/CD22 bispecific antibody (Bs20x22) maintained binding characteristics similar to the parent mAbs, 293T cells were transfected with either CD20 or CD22 and stained with Bs20x22 or a parent mAb.

A drug resistant large cell carcinoma line showed only a small reduction (10%) in nuclear binding when compared to the parent line, and this difference was not altered by VPL.

Our own SPR experiments, which measured the binding kinetics of the TCR to glycolipid-loaded hCD1d for the thioamide and carbamate analogues of α-GalCer and ThrCer, show that these molecules also display similar or poorer TCR binding kinetics compared to the parent compounds.