Sentence examples for binding to the overlapping from inspiring English sources

The midbody itself represents the last connection between the dividing cells, and KIF14 had been detected in this structure as well (Carleton et al, 2006; Gruneberg et al, 2006), possibly as a consequence of a persistent binding to the overlapping central microtubules.

It is widely accepted that HuR stabilizes transcripts by hindering destabilizing factors from binding to the same or overlapping sites.

We observed a significant reduction in IRF5 binding to the regions of overlapping IRF5 RelA peaks.

Antibodies binding to epitopes overlapping the CD4-binding site on gp120 are potent inhibitors of HIV entry, such as the llama heavy chain antibody fragment VHH D7, which has cross-clade neutralizing properties and competes with CD4 and mAb b12 for high affinity binding to gp120.

Two adjacent interactions (those with a common protein) may be mutually exclusive [ 73, 74] due to the overlapping binding interfaces on the common protein.

The repression of Psl production occurs at the transcriptional level, by binding to a region overlapping the pslA promoter [ 7].

In V. harveyi, LuxO represses its own expression, irrespective of its phosphorylation state, by binding to a site overlapping the −35 sequence of the luxO promoter, thereby preventing RNA polymerase from initiating transcription (Tu et al, manuscript in preparation).

Thus, the blockade of the hPD-1/hPD-L1 interaction by pembrolizumab occurs predominantly by binding to the C'D loop and overlaps binding to the C and C' strands to compete with the binding of hPD-L1.

Alternatively, transcription factor YY1 may modulate rSAA4 transcription by binding to a site overlapping with the NF-κB-binding site [27].

34 Both nilotinib and dasatinib efficiently block Bcr-Abl tyrosine kinase catalytic activity by binding to distinct, partially overlapping sites in the kinase domain.

The competitive inhibition of binding to overlapping epitopes has been described for antibodies to ACE.