Sentence examples for binding to the nucleic from inspiring English sources

The spatial organisation of the chromosomes in the nucleus is influenced by chromatin regions binding to the nucleic lamina, i.e., the inner part of the nucleic envelope.

7-AAD was used to monitor the dead cells through binding to the nucleic acid.

Altogether, these latter points highlight the divergence of helicases in their mode of binding to the nucleic acid.

Through quantitative PCH analysis, we find that TLR9 predominantly forms homodimers before binding to the nucleic acids and the percentage of dimers does not change upon interaction with either CpG or non CpG DNA.

This conserved His residue within the His-containing loop is necessary for proper binding to the nucleic acid template [ 33].

One early concern was that the inhibitors might block polymerases non-specifically, by binding to the minor groove of the nucleic acid substrate.

DOI: http://dx.doi.org/10.7554/eLife.03273.004 The increase in resolution obtained for the CMG in the presence of DNA provided initial, support evidence for nucleic acid binding to the complex.

By contrast, in non-viable cells with damaged membranes, non-permeant ethidium homodimer-1 enters the cells, and by binding to nucleic acids the ethidium homodimer-1 produces a bright red fluorescence.

In many cases, non-coding RNAs exert their function by binding to other nucleic acids, as in the case of microRNAs and snoRNAs.

Thus, although the binding to nucleic acids is essential for NAC activity, the affinity of isolated motifs for double- or single-stranded nucleic acids is not directly correlated with NAC activity.

In conclusion, SYTO16 proved to have a combination of favourable properties: it can be excited at 488 nm and has large fluorescence enhancement upon binding to nucleic acids, allowing the use of low, nontoxic (< 10 nM) concentrations.