Sentence examples for binding to the next from inspiring English sources

"My concern is that the Bush administration, in a weakened state politically, ends up trying to rush an agreement that in some ways might be binding to the next administration," Mr. Obama said, "whether it's my administration or Senator McCain's administration".

In eukaryotes, all ubiquitin-associated pathways are characterized by a crescent complexity, since more E2s than E1s, and more E3s than E2s exist; therefore, the number of proteins potentially involved in each step increases, as well as the specificity of binding to the next substrate [ 72].

Each ankyrin repeat consists of 33 amino acids, which form a β-turn followed by two anti-parallel α-helices and a loop binding to the β-turn of the next ankyrin repeat [ 18, 19].

The next step involves irreversible binding to the surface, multiplication of the microorganisms, and the formation of microcolonies [ 6, 9].

We next mapped ZNF703 binding to the locus of the putative target gene TGFBR2 using chromatin immunoprecipitation (ChIP) (Fig 5D).

Intriguingly, this potential ligand-binding site is located next to the region in the α6 helix that makes contacts with switch II of Rac1, suggesting that ligand binding to the C1 domain could modulate Vav1 activity.

To gain further insight into the mode of chemokine binding to HEVs, we next investigated the possible relationship between IL-6 and HEVs in the salivary glands.

Distance: distance of the binding site with respect to the next start codon Orientation: binding orientation of the TFBS Cofactors: presence or absence of other TFs bound to the same promoter Since the factors are likely to act in parallel and in a combinatorial manner, we have employed multivariate methods for determining the individual importance of each factor.

Therefore, our findings indicate that the mitotic resetting of NFAT5 contributes to ensure that its nuclear localization and binding to chromatin in the next cell cycle are induced in a stimulus-specific manner.

Since ER-retention/retrieval altered KCNE binding to HERG we next examined localization of the various KCNE subunits with respect to HERG in double-staining immunofluorescence analysis.

In order to start a new elongation cycle, the A site must be emptied to allow binding of the next aminoacyl-tRNA.