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Evidently, enough proteins or protein fragments were present in γ-FBS to propitiate their avid binding to the nascent apatite complexes that then result in the formation of the particles described as NB.
We conclude from these experiments that the positive effect of Npl3 on elongation requires both binding to the nascent RNA and its physical interaction with RNAP II, which may be inhibited by phosphorylation of S411.
It has been postulated that EMG1 promotes RPS19 binding to the nascent ribosome [21], [22].
Following cortactin binding to the nascent branch junction, we added a cortactin-mediated displacement activation step (kdis) analogous to the GST-VCA-dependent activation step (knuc).
Trf4 and other factors binding to the nascent IGS1-R transcript may enhance rDNA stability at the site of transcription, possibly by promoting the repair of DNA damage.
The function of malectin binding to the nascent glycopeptides was studied using wild-type and NHK alleles of α1AT (Chen et al., 2011; Galli et al., 2011).
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Interplay between various proteins and protein complexes docking near the tunnel exit and the hierarchy of their binding to the ribosome and/or the nascent chains is currently unknown and represents an interesting and challenging question to be answered.
In this progress, signal recognition particle (SRP) plays an essential role in binding to the signal sequence of the nascent polypeptide emerging from the ribosome and directing the polypeptide toward the proper cellular compartment (Keenan et al. 2001; Halic et al. 2004).
They largely function by binding to the 3′-UTR regions of the nascent mRNA molecules resulting in mRNA destruction or translational inhibition, thus repressing gene expression.
After nascent chain binding to the M domain, αC2 would occupy a position on the opposite side of the hydrophobic groove, oriented with its hydrophobic face toward the substrate, forming part of a protective lid.
RNA processing factors can be recruited to transcribed genes in multiple, not mutually exclusive, ways: i) by binding to the DNA template either directly or through recruiting factors, ii) by binding to processing signals present in the nascent RNA and iii) by binding to defined regions of the RNAPII elongating complex i.e. CTD [ 60].
More suggestions(16)
binding to the active
binding to the mammalian
binding to the upper
binding to the bacterial
binding to the AMP-lid
binding to the imprinted
binding to the degenerate
binding to the wild-type
binding to the cellular
binding to the extracellular
binding to the hydroxyapatite
binding to the 16-base
binding to the human
binding to the nucleobase
binding to the urinary
binds to the nascent
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