Sentence examples for binding to the most from inspiring English sources

PARP-1 binding to the most proximal element, S/MAR 1, and to three consensus motifs, AGGCC, in its own promoter (basepairs –956 to +100), could be traced by electrophoretic mobility-shift assay.

3) The expected value of DMI if binding to the most downmodulating MHC class I dominates, i.e. for each mouse: DMI (dominant)  =  MAX of DMIs of all MHC molecules in this mouse.

For the formulation of the QSAR models for large sets of diverse compounds eliciting the effects at the cell to organism levels, binding to the most abundant proteins must be analyzed and correlated with structures.

Some of these peptides were also tested for binding to the most frequent Caucasian and African MHC Class II alleles (HLA-DRB1*0101, DRB1*1501 and DRB1*0401) in different populations [ 17], they may serve as potential strong B and also T cell targets.

These findings are in line with a previously reported study by Khan and co-workers, where they have scrutinized the mechanism of ThT binding to the four most abundant serum albumin variants and found out that HSA has the highest affinity to ThT and that the intensity increased in a concentration dependent manner.

These mutations are located in the TP53 domain for binding to the DNA where most of p53 mutations in cancer have been described [ 26].

Although some studies suggest miRNAs enhance expression by binding to the promoter region, most exert their effect by binding the 3′ UTR of transcribed mRNA, thereby signaling degradation or preventing protein translation.

The DLCs, which include some PCB congeners, are characterized by high-affinity binding to the Ah receptor; most biological effects are thought to be mediated by the ligand-Ah receptor complex.

HSF1 binding to the DNA in most cases does not correlate with significant changes in gene expression (on the other hand, HSF1 controls only a subset of the genes altered by heat shock).

In contrast, with exception of Arg, all amino acids of the peptide sequence are important for high affinity binding to the integrin α5 β1 with the most dramatic reduction found for Glu and Trp, as shown by binding studies with the corresponding Ala-modified analogs.

Previous experiments showed that likely hydrophobic contacts mediate the binding to the membrane/Tic complex, as most of the protein remains within the membrane upon alkaline and urea treatments [ 12].