Sentence examples for binding to the main from inspiring English sources

Accordingly, riboprotein targeting compounds have exceptional physicochemical properties that favour binding to the main ribosome binding sites.

We show that rather than binding to the main ATPase site within dynein's AAA+ ring or its microtubule-binding stalk directly, Lis1 engages the interface between these elements.

Possibly, this site, referred to as Box6, is an auxiliary operator site that supports binding to the main high-affinity operator sites, besides the intragenic Box4 and Box5, which were identified previously as secondary operator sites (Additional file 9: Figure S6) [ 35].

In this study, we assessed the robustness of the method using: (1) drugs binding to the three main binding sites found on the α-,β-tubulin heterodimer, namely the taxol-, the colchicine-, and the vinca-binding sites, (2) drugs unrelated to tubulins and the cytoskeleton such as daunorubicin and verapamil, and (3) four cell lines found in most laboratories.

According to the results of a competition assay, the inhibitory effects of LL-37 on cell adhesion and aggregation were mediated by its preferential binding to mannan, the main component of the C. albicans cell wall, and partially by its ability to bind chitin or glucan, which underlie the mannan layer.

In addition, MAP2 interacts with actin filaments promoting neurite initiation [62], [63] and MAP2 phosphorylation alters binding to microtubules, the main mechanism of microtubule dynamic regulation (reviewed in [64]).

One possibility would be that Cd is excreted in greater amounts because of its binding to albumin, the main B-Cdinding protein in plasma [ 21].

Position 2 and 9 are the main positions determining peptide binding to the HLA-A*0201 HLA-A*0201see Fig. 1B.

The structure shows that this site is the main determinant of Lhca binding to the core.

The hydrophobic interaction between the Met181 residues and the fullerene surface is the main cause of the strong binding to the NavAb channel.

H+ transfer to Asp116 and Na+ binding to Asn112 is the main process for the formation of the (L/)M and O states, respectively.