Sentence examples for binding to the ley from inspiring English sources

The chimeric (mouse/human) monoclonal IgG1 antibody BR96 (Seattle Genetics Inc., Seattle, WA) binding to the Ley was employed.

To address this question, we generated a bsAb that bind to the LeY antigen and simultaneously carries anti-Biot Cys52+2 binding entities as disulfide-stabilized single-chain Fv additions (Fig. 8 A ). Charging with Bio-Cys-Cy5 generates disulfide-connected bsAb-payload complexes in the same manner as monospecific anti-Biotin Cys52 (Fig. 8 B ).

In fact, BV does not form a single H bond with the H epitope in binding to the type 2 Ley antigen, while only one water mediated H epitope between D349′ of the P-loop and the H epitope was seen in BV binding to the type 1 Leb antigen (Fig. 6).

In fact, the H epitope of the Leb and Ley antigens played a minor role in the binding outcomes as it does not at all participate in binding to Ley, or interacting with the Leb through a single H bond among the eleven H bonds in total.

Taken together with the established rigid nature of the Ley carbohydrate [26], the available data strongly supports the binding of the Ley antigen by the hu3S193 antibody to resemble the fit of an unbendable key into a rigid lock.

Structural characterization of the glycolipids and the study of cellular binding revealed that DC-SIGN binds to the carbohydrate moieties of glycosphingolipids with Lex and Ley structure [Fuc α1-2Gal β14(Fuc α1 3 GlcNAc] moieties.

Bruno is able to track the ley lines and believes that Susarro may be going to Paris.

Or is that hubris?" says Ga Naylor, obviously friendly enough with Mr Wiggins to drop the "ley".

The preferential binding of hu3S193 to tumor cells with high surface densities of Ley and lack of binding to normal tissues expressing lower levels of Ley suggests that this antibody is involved in carbohydrate cluster recognition as a first step in tumor cell killing.

The in vivo specificity of hu3S193 for Ley on tumor cells and no saturable binding to any normal tissue compartment [20], indicates that the presentation of Ley determinants by tumor cells is different from normal tissues.

Only the Δ5KA abolishes binding to PtdIns 3,4,5 P3.