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Although AG desacylation and binding to the hypothetical UAG receptor may contribute to AG biological activity, receptor antagonist experiments suggest a direct AG effect, through GHS-R1A binding.
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A hypothetical mechanism has been proposed by which GIPC1 binding to the auto-inhibitory domain in the C-terminal region of Syx triggers RhoGEF activity.
Electrophoretic mobility shift assays were performed to evaluate the binding of the NF-κB transcription factor to the hypothetical binding sites found in COQ7 gene.
The Arabidopsis proteins (GIs 25402830, 9665127, 15218016, and 25404859), which show strong similarity to B-block binding subunits, are the hypothetical proteins translated conceptually from the nucleotide sequences of the chromosome I [[ 30]; see also ].
Molecular docking studies were carried out in order to predict the hypothetical binding mode of these compounds to the COX-2 isoenzyme.
Molecular docking investigations performed at the hA2A AR crystal structure and at a homology model of the hA1 AR allowed us to represent the hypothetical binding mode of our derivatives and to rationalize the observed SARs.
On contig 1854, we identified two homologs of YE0979, which encodes a DNA-binding protein, and the hypothetical gene YE0980 from YGI3 harbouring a putative integrated plasmid.
We tend not to entertain the hypothetical over the real".
Therefore, it appears on the lists of transcription factors preferentially associated to daunorubicin-inhibited genes (Tables 6 and 7), although the hypothetical suppression of its binding to DNA would result in activation, rather than inhibition, of the affected gene.
This hypothetical model of XLF binding to Ligase IV is illustrated in Figure 6D(2).
Only the Δ5KA abolishes binding to PtdIns 3,4,5 P3.
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