Sentence examples for binding to the four from inspiring English sources

At acidic pHs between 5.0 and 6.4, shFcRn exhibited substantial binding to the four subclasses of human IgGs at acidic pHs between 5.0 and 6.4, but at pHs between 6.8 and 8.0, its binding was negligible binding.

The molecular mechanics/generalized Born surface area (MM/GBSA) method was used to calculate the binding free energy and identify the key residues for the ERK2 protein binding to the four inhibitors.

Upon calcium binding to the four EF-hands of CaM, a hydrophobic pocket opens in each of the two lobes of CaM, which then interact with large hydrophobic or aromatic residues from the target sequence.

Additionally, binding to the four cell lines not used in screening and enrichment was significantly less relative to binding to target cells.

Stat1 gets also activated through binding to the four distal Tyr-residues with the second to last pTyr being the most preferred activation site.

Determination of the association constant of DC8E8 binding to the four repeat tau protein isoform 2N4R and mis-disordered tau 151-391/4R sevend seven times higher affinity for mis-disordered tau than for the full-length tau isoform 2N4R.

Finally, more connected network components are under stronger selection and exhibit a greater degree of allele-specific activity (that is, differential binding to the two parental alleles).

This allowed the determination of the solution structure of a ternary complex characterized by two inhibitor molecules binding to the two zinc knuckles of the NC protein.

We demonstrate that Ca2+ binding to the two sites of a βγ-domain is interdependent and that the presence of Arg at the fifth position disables a site.

Based on these models, it was possible to confidently locate the binding to the three separate binding sites, as the small variation in the sequence within the C-repeat regions of the M1 protein generates different cross-linked peptides when cross-linking the M1 protein to albumin.

In this study, to investigate the essential amino acid residues of BTC for binding to the two receptors, we introduced point mutations into the EGF domain of BTC employing error-prone PCR.