Sentence examples for binding to the first from inspiring English sources
These modifications hinder the TRIM25 binding to the first CARD and the K-63-linked polyubiquitination of the Lys-172 of RIG-I.
As shown in Fig. 6B, a mutation of binding site 1 almost completely abolished the activity of miR-222, whereas a mutation of binding site 2 only slightly reduced miR-222 activity, indicating that the majority of miR-222 activity is due to the binding to the first consensus sequence.
Their results may represent calcium binding to the first site but not the second site.
If, as it appears, this is the case, the aggregate kon for binding to the first site, 2.0 μM–1 shouldhould be halved, to 1.0 μM–1 s–1, and thus the kon values for binding to the first and second sites are identical.
Biochemical structure and interaction studies support a model in which Slit binding to the first immunoglobulin-like (Ig1) domain of Robo receptors activates a repulsive signaling pathway in axonal growth cones.
We did not detect TCF4 binding to exon 6 of Imp1 or to the promoter/enhancer of Lgi4 (negative controls) but did detect TCF4 binding to the first intron of Axin (a positive control [ Jho et al., 2002]).
We concluded that LDLA-box 2 binding to the second 14-3-3 14-3-3 14-3-3an intriguing observation with protomer implications for ExoS regulation.
This is done in particular for a set of related sequences binding to the third PDZ domain of PSD-95 with encouraging results.
We stimulated intestinal organoids with Notch ligands and inhibitors and discovered that intestinal stem cells employ a positive feedback mechanism via direct Notch binding to the second intron of the Notch1 gene.
These findings indicate that the first nine ZFs of the BORIS DNA binding domain are required for binding to the sixth CTCF target site in the IGF2/H19 ICR in vitro.
Interestingly, the scFvs developed here showed good binding to the breast cancer cell line T47D and ovarian cancer cell line SKOV3, but no binding to the second breast cancer cell line MCF-7.
