Sentence examples for binding to the ferric from inspiring English sources
Cyanides are highly toxic due to their binding to the ferric form of vital cellular enzymes such as cytochrome oxidase, succinic dehydrogenase and superoxide dismutase, with particular interest on the electron transport system in the mitochondria [7].
It has been proposed that hxHbs might destroy NO through a mechanism that includes binding to the ferric heme iron [38].
Rapid mixing experiments measuring NO binding to the ferric protein were conducted with a BioLogic SFM 400 stopped-flow reactor coupled to a MOS 250 spectrophotometer.
This is probably due to intramolecular His binding to the ligand binding site, which is enhanced in the ferric oxidation state [81].
Previous studies have shown that the truncated form of Ggly, the octapeptide LE5AY, was still biologically active in vitro, and that activity was dependent on ferric ion binding but independent of binding to the cholecystokinin 2 (CCK2) receptor.
Manipulation of the (distal) heme cavity architecture is often reflected by changes in both binding rates as well as in the strength of binding of cyanide to the ferric heme iron.
For studies on cyanide binding to ferric wild-type NdCld and the mutants, the conventional stopped-flow mode was used, and the decrease of the absorbance at the respective Soret maximum was monitored.
Apotransferrin, upon binding to ferric ion, forms transferrin, which binds to transferrin receptor on the cell surface and enters the cell by receptor-mediated endocytosis [28].
The findings suggest that (i) chlorite binding to ferric NdCld occurs spontaneously and (ii) that Arg173 is important for recognition and to impair hypochlorite leakage from the reaction sphere.
Consequently, we have limited ourselves to NO binding to ferric heme in this work.
The conserved and (as the X-ray structures suggest) mobile distal arginine supports binding of the anionic chlorite to the ferric resting state of Cld.
