Sentence examples for binding to the external from inspiring English sources

In 2010, David Julius of the University of California in San Francisco and his colleagues reported that a toxin isolated from the venom of the Earth Tiger tarantula acts by binding to the external portion of the heat-sensitive TRPV1 protein and trapping the pore in its open state.

Selection of VHHs by phage display, with specific elution of bound phages with the external antigenic DNA, shows that selected private anti-Id VHHs compete for binding to the external antigen and bear a functional mimicry of the DNA.

Als3 is a hyphal-associated adhesin and invasin in C. albicans and is essential in ferritin-binding to the external hyphal layer [ 42].

AGE-coordinated Cu (II) almost certainly remains catalytically active, and could therefore bind to the external, high-affinity Cu (II -binding sII -binding near the NH2-terminusite CTR1 [ 79].

The confirmation of protein binding to the lipoplexes external layer without either destabilizing the multilamellar structure [ 11], or dissociation [ 6, 10, 21] was previously reported.

External binding to the major or minor DNA grooves can be responsible for the observed disturbance on DNA conformation [ 32, 33].

This reparameterization shows that the two variant assumptions on the Ca2+ binding to the uniporter (Case 1 and Case 2) are indistinguishable from each other, indicating that the external and internal Ca2+ binding constants for the uniporter may be equal (Case 1).

The fitting of the RBD to the upper protrusion was unique so far as it was the only position, which allowed the exposure of both receptor-binding sites to the external surface of the trimer.

AIP1 could bind only non-modified histones or, most probably, the internal folding of the protein and/or the binding to an external molecule may regulate different active states where AIP1 can bind histones in a selective way.

This suggests that H+ binding to an external site on the TRPV1t channel protein modulates the affinity of TRPV1t agonists, including that of MRPs, to their respective intracellular binding sites on the channel protein.

The rules were selected based on the MetaNetX binding to external databases and the iJO1366 whole-cell E. coli metabolic model [43].