binding to the endogenous

USAGE SUMMARY

The phrase "binding to the endogenous" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in discussions about biochemical interactions or pharmacology. Example: "The drug is effective due to its ability to bind to the endogenous receptors in the body."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

11 human-written examples

By binding to the endogenous site, Zn2+ acts as a potent non-competitive inhibitor of dopamine uptake mediated by the hDAT transiently expressed in COS-7 cells.

Life Sciences

As shown in Fig. 4, there was marked enrichment of palladin binding to the endogenous SMA promoter region in both A404 and R518 cells (p<0.05).

Plosone

Moreover, no binding of these two proteins in the Xenopus haemoglobin promoter which lacks Pax2 and Sox2 binding sites was detected, confirming the specificity of Pax2 and Sox2 binding to the endogenous Xenopus HCNR 81675 (Figure 6B and quantitative PCR results shown in Figure 6C).

Plosone

This was tested by luciferase reporter assays in the AR-negative cell line to avoid binding to the endogenous protein.

British Journal of Cancer

By presenting the antigen in its native conformation for immunisation and hybridoma selection, this procedure promotes the generation of antibodies capable of binding to the endogenous protein.

BMC Biotechnology

Furthermore, antibodies generated against a purified recombinant protein are frequently incapable of binding to the endogenous protein in its native context.

BMC Biotechnology

Human-verified similar examples from authoritative sources

Similar Expressions

49 human-written examples

To our surprise, however, pS3291-BRCA2 was barely detectable in the Rad51 immunocomplexes from the soluble fraction, suggesting that an as-yet-unknown mechanism may interfere with Rad51 binding to the pool of endogenous BRCA2 that is physiologically phosphorylated at S3291, despite the presence of additional Rad51-binding BRC motifs in the middle region.

Cell Reports

The study results suggest that after P140 peptide binding to HSC70, the endogenous (auto antigen processing might be greatly affected in MRL/lpr antigen-presenting B cells, leading to the observed decrease of autoreactive T-cell priming and signalling via a mechanism involving a lysosomal degradation pathway.

Annals of the Rheumatic Diseases

Chromatin IP has confirmed Smad4 binding to the SBE region in the endogenous LAMA3 promoter [ 19].

BMC Cancer

This probe has capacity of tightly binding to the APN for imaging endogenous APN in living human ovarian clear cell carcinoma cells (ES-2) and has potential application in biological study of cellular APN.

Chinese Chemical Letters

Myc binding to miRNA loci occurred to the same extent as endogenous binding to the Myc target gene HirA (Chen et al, 2008; Kim et al, 2008).

EMBO Journal

Expert writing Tips

Best practice

When describing molecular interactions, be precise about the type of "binding" (e.g., covalent, non-covalent) for clarity.

Common error

Avoid implying that "binding to the endogenous" confirms a highly specific interaction without supporting evidence; further investigation is often needed to rule out non-specific interactions.

Linguistic Context

The phrase "binding to the endogenous" functions as a prepositional phrase often used to describe the interaction between a substance and a naturally occurring component within a biological system. Ludwig AI indicates that it's grammatically correct and usable, mostly in scientific contexts.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, "binding to the endogenous" is a grammatically sound prepositional phrase primarily used in scientific contexts to describe interactions with naturally occurring biological components. Ludwig AI confirms its correct usage, although its frequency is relatively uncommon. When using this phrase, ensure clarity regarding the specificity and nature of the interaction. Related terms include "interacting with" or "attaching to" the endogenous component. Remember that while grammatically correct, the phrase's impact is maximized with precise descriptions of the "binding" type and its implications.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

binding with the endogenous

Replaces 'to' with 'with', altering the prepositional relationship but maintaining the core meaning of interaction.

interacting with the endogenous

Replaces 'binding' with 'interacting', emphasizing a broader range of associations rather than a specific binding action.

attaching to the endogenous

Substitutes 'binding' with 'attaching', focusing on the physical connection aspect.

connecting to the endogenous

Replaces 'binding' with 'connecting', highlighting a link or association.

linking to the endogenous

Uses 'linking' instead of 'binding', suggesting a connection or relationship.

associating with the endogenous

Employs 'associating' to convey a more general relationship or connection.

complexing with the endogenous

Replaces 'binding' with 'complexing', emphasizing the formation of a complex.

adhering to the endogenous

Substitutes 'binding' with 'adhering', focusing on the property of sticking or clinging.

reacting with the endogenous

Uses 'reacting' to imply a chemical interaction or response.

interacting specifically with the endogenous

Adds 'specifically' to emphasize a targeted interaction.

FAQs

How can I use "binding to the endogenous" in a sentence?

You can use "binding to the endogenous" to describe the interaction of a substance or molecule with a naturally occurring component within a biological system. For example, "The drug's efficacy is due to its "binding to the endogenous" receptors in the brain".

What's a good alternative to "binding to the endogenous"?

Depending on the specific context, alternatives include "interacting with the endogenous", "attaching to the endogenous", or "complexing with the endogenous".

Is it correct to say "binding with the endogenous" instead of "binding to the endogenous"?

While "binding with the endogenous" might be understood, ""binding to the endogenous"" is the more standard and grammatically preferred phrasing, especially in scientific literature.

In what contexts is the phrase "binding to the endogenous" most commonly used?

The phrase ""binding to the endogenous"" is predominantly used in scientific and medical contexts, particularly in discussions related to biochemistry, pharmacology, and molecular biology, where interactions with naturally occurring molecules are discussed.