Sentence examples for binding to the end from inspiring English sources
The Mre11/Rad50/Xrs2 complex initiates IR repair by binding to the end of a double-strand break, resulting in 5' to 3' exonuclease degradation creating a single-stranded 3' overhang competent for strand invasion into the unbroken chromosome.
These data suggested that PTB binding to the 5' end of the FCV genomic RNA is required for optimal virus replication.
Results from the ISS/T6 mutation clearly indicate the importance of PTB binding to the 3' end of I4 for the regulated splicing of fos B pre-mRNA.
These results together with those of the PTB binding assays and in vitro and in vivo splicing assays established a strong correlation between PTB binding to the 3' end of fosB I4 and intron retention.
miRNAs are small, non-coding sequences of 17 25 bp that regulate gene expression by binding to the 3' end of target mRNAs, resulting in the inhibition of translation of the mRNAs [2], [3].
In summary, it appears that PTB and U2AF65 may compete for binding to the 3' end of fosB I4 thus providing an additional level of regulation for the splicing of the fosB pre-mRNA.
The data suggest that competition between different SS enzymes for binding to the ends of growing linear chains is an additional factor important for the determination of amylopectin structure.
The 5' end of the ssDNA was blocked by anti-digoxigenin antibody, which can prevent MutL from binding to the ssDNA end and from dissociating from the end (Fig. 2B cartoon).
We speculate that the comet-like barbed end localization of GFP-LZ-Lpd850−1250aa may reflect dimers simultaneously binding to the barbed end and near the barbed end, creating a fluorescent speckle.
We speculate that the comet-like barbed end localization of GFP-LZ Lpd850-1250aa is possibly due to dimers simultaneously binding to the barbed end and near the barbed end, which effectively creates a fluorescent speckle.
LEDGF IBD fusions to each member of the NELF complex and SPT5 were also constructed (Supplementary information, Figure S1H) for use as control markers for binding to the 3′ end of snRNA genes, 3′ end of replication-dependent histone genes, and promoter proximal regions of genes with polyadenylated messages.
