Sentence examples for binding to the downstream from inspiring English sources

PTB binding to the downstream domain of In100 plays an important role [10].

Sp1 binding to the downstream site regulates the expression of APEX in a cell cycle dependent fashion [75].

This would result in varying degrees of the dFOXO binding to the downstream genes.

Interestingly, the phosphorylation of three Tyr residues on the β-hairpin would disrupt the structure and lead to the binding to the downstream Nck2-SH2 domain for signal transduction.

The PAX8 mutation was normally located to the nucleus and showed a normal transactivation of and normal binding to the known downstream targets.

At first glance, the fact that the block to transcriptional elongation occurs when tight binding to the nucleosome is downstream of the dyad seems counterintuitive.

Hypothetically, Pb could alter ACTH-dependent CORT release by affecting ACTH binding to the melanocortin receptor or the downstream pathways that lead to CORT release (Doufexis et al. 2007; Halkerston 1975), but further studies are needed to really understand our findings.

In ethylene-dependent fruits, ERF, as the final response gene in ethylene signaling pathway, directly regulate fruit ripening by binding to the promoters of their downstream genes, including ACO, ACS, PG, EXP, and PSY (Han et al. 2016; Lee et al. 2012; Liu et al. 2014).

Insulin binding to the insulin receptor activates downstream signaling that leads to the translocation of GLUT4 from the intracellular compartments to the plasma membrane where it performs glucose transport [4] [6].

OsMYB103L is a putative R2R3 MYB transcription factor, which is expected to regulate gene expression by binding to the promoters of its downstream genes.

Hence, future studies will focus on determining whether TS protein regulates the expression of these genes directly by binding to the mRNAs or indirectly through downstream mechanisms.