Sentence examples for binding to the distinct from inspiring English sources

Together, these studies on seasonal and pandemic influenza strains have provided a comprehensive understanding of how high-affinity binding to the distinct topology of 'long' α2,6 linked sialylated glycans is a necessary step in efficient aerosol transmission (Additional file 1).

In order to provide further evidence for the induction of the gp41 six-helix bundles by the distinct ligands binding to the HIV envelope, the newly formed structures in virus lysates were also quantitated by a sandwich ELISA [ 21].

Similarly, intravenously injected ESTA-1 demonstrated distinct binding to the tumor vasculature in a breast cancer xenograft model.

Although binding to the same LBP, different ligands induce distinct functions of RXRα, which is due to the distinct conformational changes of RXRα induced by different ligands (Altucci et al., 2007; de Lera et al., 2007; Perez et al., 2012).

We modified vaults by the addition of a 33 aa peptide (z) derived from staphylococcal protein A to the C-terminus (hereafter referred to as cp-MVP-z) that binds the Fc portion of immunoglobulins at a site distinct from binding to the Fc receptor (FcR) [26].

CENP-C has been shown to discriminate CENP-A from H3 nucleosomes by binding directly to the distinct C-terminus of CENP-A and docking via acidic patches on histones H2A and H2B [ 34,35].

It seems that their doses, posttranslational modifications, their binding to the different receptors may lead to distinct functional outcomes.

We have identified thirteen distinct drug-like molecules binding to the JAK2.

Interestingly, GM1 and GM3 are concentrated in membrane areas that markedly differ in membrane curvature (Ref. 143), so that on binding to distinct gangliosides, the same amyloid protein could adopt distinct conformations.

The antagonist/agonist activity of some antiandrogens is thought to be due to different actions on the AR receptor whereby the AR is simultaneously stimulated by binding to a distinct domain of the receptor (Tamura et al. 2006).

CD28 deficiency is due to a transcriptional block resulting from the loss of nuclear transcription factors binding to two distinct regulatory motifs in the promoter region of the CD28 gene [ 14].