Sentence examples for binding to the cytoskeleton from inspiring English sources
Its transmembrane binding to the cytoskeleton is regulated via tyrosine phosphorylation (pY892) of β-dystroglycan.
This fixation and staining method should reveal total EB1 molecules, in contrast to the cold methanol method, which only reveals EB1 molecules binding to the cytoskeleton.
Altogether these findings quantitatively demonstrate for the first time that L-plastin contributes to the fine-tuning of actin turn-over, an activity which is regulated by Ser5 phosphorylation promoting its high affinity binding to the cytoskeleton.
A shift to an open conformation is required for binding to the cytoskeleton.
Movement of mitochondria relies on their binding to the cytoskeleton through adaptors and Miro is a key regulator in Ca2+-mediated mitochondrial stopping.
A particle or agent based simulation allows exploring the effects introduced by the spatial organization of the cell including (transient) binding to the cytoskeleton.
These results will allow the design of LSP1 mutants that do not bind to the cytoskeleton to determine the importance of LSP1 cytoskeleton binding for the diverse functions of LSP1.
We then designed a novel cell-free cytoskeleton binding assay in which a set of GST LSP1 fusion proteins are allowed to bind to the cytoskeleton in NP-40 soluble lysates of BW5147 cells and are recovered in the low-speed detergent insoluble pellet.
These data showed that clustering of ICAM-1 promotes binding to the actin cytoskeleton, possibly through filamin A or B. To determine whether the intracellular tail of ICAM-1 is required for the shift of clustered ICAM-1 to the immobile fraction, we used an ICAM-1-GFP mutant that lacks the intracellular domain (ICAM-1-ΔC-GFP).
Besides binding to the actin cytoskeleton, 4.1N selectively interacts with the membrane proximal region of GluA1, but not GluA2 54, 54.
We propose that eEF1A is limiting in cells and this pool is partitioned between binding to the actin cytoskeleton and being free to deliver aminoacyl-tRNAs to the ribosome.
