Sentence examples for binding to the core from inspiring English sources

These data suggest that although binding to the core stabilizes the E3 dimer interface, it does not play a significant role in reducing the sensitivity of the A. suum PDC to NADH inhibition during anaerobiosis.

It should be noticed that when switching the thiolate R group to methyl (to reduce computational cost), attention should be given to the effect that this change introduces to the stability of the shell structure, and in turn, to the shell binding to the core of the NC.

In this study, we show that protein binding to the core motif is necessary but not sufficient for transcriptional activation by the delta E3 element.

About 30-nt downstream of Inr is the Downstream Promoter Element (DPE), which is recognized by the TBP-associated factor (TAF) to enhance TBP binding to the core promoter (Burke and Kadonaga, 1997).

Contrary to the reported data in yeast demonstrating that iron reversibly increase the binding of Yfh1 to Isu1/Nfs1 [11], under similar experimental conditions, we did not observe any increase nor decrease of FXN binding to the core complex (Fig S4A B).

Next, to determine whether specific amino acids are required for binding activity, alanine substitution of individual amino acids across this core element was conducted and the resulting peptides were reacted with WT Bves. Figure 2D shows that lysine to alanine substitution at positions 272 and 273 eliminates Bves binding to the core element peptide.

In older mice the plaques were larger and HS-68 emission was markedly blueshifted when binding to the cores and the surrounding diffuse amyloid structures, rendering green-colored deposits.

RUNX1, also called AML1, encodes the alpha subunit of the core binding factor (CBF), which binds to the core element of many enhancer and promoter DNA regions.

The structures of human PDK1 and PDK3 with AZD7545, dichloroacetate, and radicicol (antitumor compound) revealed that AZD7545 binds to the lipoyl-binding pocket in the N-terminal region of PDK1 and prevents PDK1 from binding to the E2·E3BP core, while radicicol binds to the nucleotide-binding site of PDK3 and inhibits its activity by competing with ATP for the nucleotide-binding site.

We first confirmed whether anti-MUC1 antibody (CD227) is reliable enough to report changes in antibody binding to the peptide core whether in response to inhibition of O-glycosylation, or shedding of glycosylated functional groups from the core protein.

Anti-sigma factors bind to their cognate sigma factors in some cases, inhibiting their binding to the RNAP core enzyme.