Sentence examples for binding to the compound from inspiring English sources

Mutations of BCR- ABL that fix the kinase domain in its active configuration result in diminished binding to the compound and, therefore, a loss of inhibitory potency.

Some proteins may bind to metabolites but show negligible binding to the parent compound (Hamers et al. 2008).

Mutation of the central glutamate sidechain of Cass2 had little effect on its strength of binding to the monovalent compounds tested (TPP, benzalkonium chloride).

Apparently both parallel and antiparallel amyloid β-sheets are effective in binding to the same compounds.

These pharmacophores explain the selectivity of binding to the MATs for various compound classes and have been used to search in silico databases for novel, potentially selective ligands.

This information facilitated the in silico screening of a library of compounds in that the computational evaluation of chemical compound binding to the target protein could be analyzed in greater detail.

It was first necessary to ensure that the time of incubation of oocytes with inhibitor was sufficient to allow compound binding to the MCT to reach equilibrium.

The development of the compounds preferentially binding to the specific DNA sequence is one of the potential but very difficult approaches in this strategy.

The discrepancy of comparatively weak inhibition of rhodamine B efflux and strong interaction with the transporter protein ATPase by verapamil could thus be explained with little interference of the compounds when binding to the Abcb4 binding site.

NMR experiments confirmed binding to the A-site for some compounds.

Therefore, molecular docking simulations were performed to calculate the receptor-ligand interactions of our synthesized compounds binding to the CB2 receptor.