Sentence examples for binding to the complementary from inspiring English sources
MicroRNAs (miRNAs) are small noncoding RNAs that modulate gene expression post-transcriptionally by binding to the complementary sequences of targeted mRNAs.
MicroRNAs participate in post-transcriptional regulation of cellular differentiation by binding to the complementary sequences of target messenger RNAs (mRNAs) or non-coding RNAs and down-regulate their target gene expression.
The presence of An14g04280, An03g01620 and An07g00780 expression constructs was confirmed by PCR using the JS_XlnDp_FW primer, binding to the promoter region of the construct, and JS_gatA_RV, JS_gatB_RV or JS_gatC_RV specifically binding to the complementary strand in the corresponding coding region.
In eukaryotes, miRNAs can regulate gene expression by binding to the complementary sites in 3′-UTR sequences of their target genes (2).
miRNAs work by highly specific binding to the complementary site on the mRNA target and are being considered as new therapeutic strategies.
They inhibit translation by partially or totally binding to the complementary 3' UTR of their target mRNAs within the multiprotein RNA-induced silencing complex (RISC).
By binding to the 3' UTR of complementary protein-coding mRNAs, miRNA primarily acts in the post-transcriptional repression of gene expression in animals and plants.
MicroRNAs (miRNAs), which belong to a class of highly conserved and small non-coding RNAs, are approximately 22 25 nucleotides in length and abundant in animals, plants and even in viruses. 1 2 Mature miRNAs negatively regulate target gene expression at the post-transcriptional level by binding to the 3′-untranslated complementary sequence of target mRNA.
smRNAs regulate gene expression by binding to the target mRNAs through complementary base-pairing [ 11].
These lncRNAs could therefore act as negative regulators of gene expression by complementary binding to the UTRs of target mRNAs (fig. 3).
5' end sequences are critical for miRNA function [2], [41], [71] [73] and the seed region is thought to contribute to target recognition by perfect (or near perfect) complementary binding to the mRNA target site.
