Sentence examples for binding to the cap from inspiring English sources

Those two residues were shown to be important for Ago interaction with GW182 rather than binding to the cap in both human and flies (Eulalio et al., 2008).

Moreover, fly Ago-RISC associated with target mRNA in a manner independent of GW182 and repressed translation without affecting eIF4E recognition of the cap (Fukaya et al., 2014), further arguing against the idea that Ago binding to the cap is required for translation repression.

To assess directly whether CUG bound ribosomes required binding to the 5' cap, we carried out toeprint analysis in the presence of m7GTP cap analog which competes for binding to the cap binding protein, eIF4E.

While it is not readily clear why eIF4E binding to the cap structure in these weakly translated mRNAs is inefficient, some of these mRNAs appear to have an extensive 5'UTR secondary structure [10].

After binding to the cap, eIF4F unwinds the mRNA 5′-proximal secondary structure to facilitate the binding of the 43S preinitiation complex (see below).

The mutations on β5 may define the right-hand limit of VPg binding to the cap-binding pocket of pea eIF4E.

With one K+ bound the G-quadruplex was stable, without apparent conformational changes detected till the second K+ beginning binding to the bottom cap at 159.30 ns (Fig. 2D).

The position of the stem loop secondary structure in the TGF-β1 5'UTR suggests that it is most unlikely to act via steric hindrance of 43S pre-initiation complex binding to the m7G cap structure.

The eukaryotic translation initiation factor 4E (eIF4E) plays an important role in regulating gene expression because eIF4E binding to the mRNA cap is a control point for translation.

For instances, DDX3X has been reported to bind to the cap-binding protein complex (Shih et al, 2008).

The mRNA cap binds to the cap-binding protein (CBP) complex, which regulates mRNA transport from the cytoplasm to the nucleus.