Sentence examples for binding to the bacterial from inspiring English sources

Telithromycin was derived by structural modification of the basic macrolide molecule to allow tight binding to the bacterial ribosome that enhances potency and minimizes the risk for the development of resistant strains.

IdeS generated 1/2Fc fragments do not compete efficiently with intact IgG in binding to the bacterial surface and rapid dissociation of 1/2Fc allows binding of new IgG.

Several classes of antibiotics function by binding to the bacterial ribosome and inhibiting bacterial protein synthesis.

The aminoglycosides used in the treatment of bone infections belong to the protein synthesis inhibitor family of antibiotics, binding to the bacterial ribosomal 30S subunit to achieve a bacteriostatic effect through transcription errors during cell division [11].

The objective is to find proteins eliciting antibodies capable of binding to the bacterial surface, and through interaction with the complement system kill certain pathogen microorganisms.

These proteins act as opsonins by binding to the bacterial cell surface, facilitating interaction with specific phagocyte receptors, as well as promoting bacterial engulfment [68] [70].

The most potent compound 17BIPHE2 appears to kill bacteria by damaging bacterial membranes, which may also involve the access and binding to the intracellular bacterial DNA.

The mechanism for macrolide resistance in M. pneumoniae is point mutations in a few positions of domain V of the peptidyl transferase loop of 23S rRNA, the location of macrolide binding to the 50S bacterial ribosome subunit (3 ).

At this stage, it can only be speculated that bacterial binding to the multifunctional protein favours bacterial survival and/or traversal following cell entry.

To assess whether CEACAM mutations that either significantly increase or decrease bacterial binding to the soluble constructs also affect bacterial binding to cell-expressed receptor constructs, we analysed COS cells transiently transfected with CEACAM1-4L containing Q89A, Q89N and I91A substitutions.

Linezolid is the first member of an entirely new class of antibiotics that can inhibit bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome via interaction with the 23S rRNA of gram-positive bacteria [ 1].