Sentence examples for binding to the aryl from inspiring English sources

Since TCDD acts through binding to the aryl hydrocarbon receptor (AHR), and the AHR has been identified as an important factor in ovarian function, we also conducted experiments to confirm the presence and activation of the AHR in our tissue culture system.

TCDD has been shown to operate in animals and humans through binding to the aryl hydrocarbon receptor (AhR, [ 5]).

The compound has been shown in human and animal studies to alter transcription of genes by binding to the aryl hydrocarbon receptor (AhR).

Furthermore, some of the PCBs have dioxin-like activity and therefore, through binding to the aryl hydrocarbon receptor (AhR) (Pocar et al. 2005), indirectly modify sex steroid action.

Planar, hydrophobic 2- 4-aminophenyl benzothiazoles fulfil structural requirements for binding to the aryl hydrocarbon receptor (AhR), and are potent AhR agonists (Loaiza-Perez et al, 2- 4-aminophenyl benzothiazoles

Cytochrome P450 1A (CYP1A) induction is elicited by PAHs and PHAHs via binding to the aryl hydrocarbon receptor (AHR) (Whitlock 1999).

Furthermore, dioxin-like compounds exert their effects through binding to the aryl-hydrocarbon receptor, which is thought to antagonize peroxisome proliferator activated receptors (9).

Upon ligand binding, the AhR binds to the aryl hydrocarbon nuclear translocator (ARNT) protein, resulting in translocation to the nucleus, where the ligand AhR ARNT complex binds to response elements in the promoter of AhR-regulated genes (dioxin response element).

Mechanisms of fetal toxicity of PAHs are not fully understood but may involve the induction of apoptosis after DNA damage from PAHs, antiestrogenic effects of PAHs, and binding to the human aryl hydrocarbon receptor to induce P450 enzymes or to receptors for placental growth factors, resulting in decreased exchange of oxygen and nutrients (Dejmek et al. 2000).

All DLCs share a typical planar structure, which leads to an elevated binding affinity to the aryl hydrocarbon receptor (AhR).

First, the TEFs of PCBs are based on their relative "dioxin-like" binding affinity to the aryl hydrocarbon receptor (AhR).