Sentence examples for binding to the appropriate from inspiring English sources
This unusual shape prevents ribosomes--the button-shaped organelle that zips along the messenger RNA and strings together amino acids into proteins--from binding to the appropriate piece of RNA.
Activation of the pathway is initialized by an agonist binding to the appropriate GPCR which has greater affinity for the Gs protein.
The predicted CTL epitopes were synthesized and tested by biochemical methods for binding to the appropriate recombinant HLA-I protein, and by IFNγ ELISPOT analyses for CTL immune responses using PBMC from healthy, adult and HLA-typed Danish subjects, assumed to have been exposed to multiple influenza infections during the past.
The optimal activation of NF-κB, allowing its binding to the appropriate promoter regions, requires phosphorylation in the transactivation domain of the p65 protein.
It is widely assumed that G protein-coupled receptors and among them, the melatonin receptors, share the same structure as rhodopsin in which predicted critical residues for ligand binding to the appropriate binding pocket are located in the transmembrane regions [ 29].
Upon binding to the appropriate ECM ligand, β1 undergoes conformational changes and its short cytoplasmic tail recruits several cytoplasmic proteins that oligomerize into focal adhesion structures to connect extracellular components, such as fibronectin (FN), collagen and laminins, with signaling components of the cytosol and intracellular actin cytoskeleton [ 15].
In terms of investigating receptor biosynthesis after ligand stimulation again the appropriate ligand binding to the antibody-receptor complex is necessary.
> -wrap-foot> To gain an understanding of the extent to which the free glycopeptides in solution exist in conformations appropriate for binding to the BtOGA, independent MD simulations (500 ns) were performed on each of the five glycopeptides.
Due to daptomycin's requirement of calcium to be present for effective binding to the bacterial membrane, susceptibility testing requires appropriate supplementation of calcium to simulate levels found in human serum (45 55 mg/L) [ 14- 16].
MicroRNAs (miRs) represent small non-coding RNAs of about 20 to 22 nucleotides, which, upon sequence-specific binding to appropriate mRNAs, repress the translation of the corresponding proteins or induce a subsequent degradation of the miR/mRNA complexes.
Like the majority of neoplastic cells, HCC secrete an array of inflammatory cytokines that exert their multiple, partially overlapping functions (mitogenic, motogenic, angiogenic) in a para-/autocrine manner via binding to their appropriate receptors.
