Sentence examples for binding to the affinity from inspiring English sources

The sieving capability of the NIPAm shell shields the core and its affinity bait groups from larger molecules that may be present and could compete with the intended low-abundance, low molecular weight molecular targets for binding to the affinity bait in the core.

Second, the large number of proteins in ME1 suggested that there was significant amount of non-specific binding to the affinity beads.

These results suggest that rDGAT1 may be folded in a way to prevent MBP fusion partner from binding to the affinity resin.

Another improvement is the use of synthetic eTHF as an internal standard to account for any loss of folate during extraction and subsequent binding to the affinity column.

The purifications were performed in the absence and presence of benzonase to exclude DNA-mediated interactions and a cell line containing only the empty vector was used to control for non-specific binding to the affinity matrix.

Elution profiles of phages modified with the specific affinity motifs (compared to non-specific phages) document their binding to the affinity resins and effective elution with standard competitive agents.

Direct binding studies with K1374R demonstrated no significant alteration in binding to the lower affinity site; however, binding to the high affinity site is reduced by 83%.

Mutation of Lys-1370 to Ala resulted in a 4-5-fold increase in the Kd for binding to the lower affinity site with no significant alteration in binding to the high affinity site or signal transduction properties.

In vitro findings also confirmed the tracer's binding to the high-affinity state of D2/3R.

In radioligand binding assays, des-CIC and fluticasone exhibited similar high-affinity binding to the glucocorticoid receptor, whereas ciclesonide exhibited 100-fold less binding affinity than fluticasone [19].

Hence residues within this segment may be important for the kinetics of DNA binding, and indirectly contribute to the binding affinity.